Does a Salmon Sperm Facial Really Work?

The beauty world has never hesitated to explore the unconventional – from snail mucin and bee venom to placenta extracts and fermented rice. Now, salmon sperm has entered the spotlight. Marketed as the next frontier in anti-aging skincare, the salmon sperm facial is making its way from cutting-edge dermatology clinics in Seoul to luxury spas worldwide. But beyond its “viral” novelty, does the science support the claims?

A salmon sperm facial treatment uses an ingredient called polydeoxyribonucleotide (PDRN), which is extracted from the milt (sperm sacs) of sustainably farmed salmon, most commonly Oncorhynchus mykiss (also known as rainbow trout).

For those concerned about the ethics of extracting PDRN, the process does not require killing the fish, and the extraction is often done during existing salmon harvesting operations, meaning the material is collected from byproducts that would otherwise be discarded.

Originally developed for medical wound healing, PDRN has gained popularity in cosmetic dermatology for its regenerative properties. When applied topically or injected into the skin, PDRN can promote cellular repair, reduce inflammation, and stimulate collagen production. Some facials incorporate microneedling or mesotherapy to help the ingredients penetrate more deeply.

So, does a salmon sperm facial really work? While more long-term clinical studies on its cosmetic use are still emerging, existing research on PDRN shows encouraging results. Here’s a more detailed breakdown of the most frequently reported benefits, backed by science.

PDRN helps enhance the skin’s moisture retention by promoting cellular repair. Studies have shown that PDRN can stimulate tissue regeneration and improve skin elasticity and hydration, especially when used after laser resurfacing or microneedling procedures.

PDRN stimulates the cells responsible for producing collagen and elastin, leading to firmer, more youthful skin over time. Clinical studies have shown its efficacy in improving skin density and reducing fine lines through enhanced collagen synthesis.

Through its regenerative and anti-inflammatory actions, PDRN can contribute to a more even skin tone and reduce hyperpigmentation. Its ability to accelerate cell turnover helps fade discoloration and supports a healthier skin barrier.

Initially developed for treating chronic wounds, ulcers, and burns, PDRN is now used in aesthetic dermatology for its healing capabilities. It reduces inflammation, accelerates tissue regeneration, and shortens post-procedure downtime, especially when used after laser treatments or microneedling.

While clinical data is still growing, dermatologists in South Korea (where the treatment is especially popular) often pair it with lasers or other treatments for enhanced results.

However, it's worth noting that visible improvements usually require multiple sessions, and results tend to be more subtle than dramatic.

Despite its fishy origins, the salmon sperm facial is generally well-tolerated. PDRN is biocompatible with human skin, meaning it’s not harmful to living tissue, and allergic reactions are rare. Depending on the application method, you may experience temporary, minor side effects.

• Topical facials: These are the least invasive and usually come with minimal risk.
• Microneedling or injection-based versions: Expect temporary redness, mild swelling, or pinpoint bleeding, similar to other collagen induction therapies.

As with any skin treatment, it's best to consult a dermatologist, especially if you have sensitive skin or a compromised barrier. More importantly, ask about which products you can and cannot use right after your treatment.

Once you get clearance from your doctor, add POND'S Age Miracle Ultimate Youth Day Cream and POND'S Age Miracle Ultimate Youth Night Cream to your skin rejuvenation routine. These contain hexyl-retinol, which boosts collagen and speeds up skin repair for stronger, plumper skin.

Prices vary widely depending on where you get your treatment and the method used, usually going from P12,000 to P35,000 per session. Some clinics offer packages or combine PDRN therapy with other treatments like PRP or laser resurfacing for better value.

While not a miracle cure, the salmon sperm facial can offer meaningful improvements in hydration, radiance, and skin texture, especially when incorporated into a consistent regimen. For those open to high-tech (and high-end) treatments, it’s a compelling, if unconventional, option to explore.